Entrepreneurship in The System of Resources for The Urban Agglomeration Development: The Case of Krasnodar City Agglomeration

Entrepreneurs, as a rule, are one of the significant subjects in the urban agglomeration development. Agglomeration effects create new business opportunities. However, analysis of specific situations does not always confirm these theoretical provisions. The results of the study conducted by the authors in the form of an expert survey to identify the problems and resources of the development of Krasnodar city agglomeration show that the development business is the most active participant and stakeholder in this project. At the same time, companies operating in this area prefer not to take their interests into the public space, but to implement them as part of lobbying activities at the level of regional authorities and municipalities. The interests of entrepreneurs representing other sectors of the economy are latent, and entrepreneurs, being potential beneficiaries of the systemic agglomeration development project, at this stage do not act as an independent entity. Opportunities and risks for most entrepreneurial structures (primarily small and medium-sized businesses) are not aggregated and articulated, which does not allow them to become a driver of agglomeration processes

Project Management in State Authorities of Subjects of The Russian Federation: Development Factors and Resources

The article describes the Russian experience in the implementation and development of the project approach in the public administration system at the federal and regional levels. The authors characterize the two-level institutional design of the project management system in the Russian Federation in the form of strategic design and project management. At the same time, the authors note that the greatest variability and riskiness is represented by the project management subsystem, which at the level of the constituent entities of the Russian Federation has a poly-variate character. Based on the results of the empirical study, the authors have identified the factors of an institutional and subjective nature that affect the success of the implementation of project management in the constituent entities of the Russian Federation. The authors also describe a set of resources for the development of a project approach in regional authorities and local self-governments of the Russian Federation: political and administrative, socio-economic, communication-network, personnel

Sustainability challenges and drivers of cross-border greenway tourism in rural areas

Funding Information: Funding: This research was funded by the BA School of Business and Finance (Latvia), internal grant number “BA 2019/1” under the research project “Management of circular business models and projects within economy of Latvia”. Publisher Copyright: © 2020 by the authors.This article provides a practical example of the development of cross-border tourism and its link to achieving sustainable development goals. Greenways (GWs) are successful and recognized initiatives in Western Europe, but have recently also shown development trends in Eastern Europe, notably, in the Baltic Sea Region and Russia. These initiatives improve the quality of life and provide opportunities for sustainable economic activities for the local communities, especially in rural areas, adding value to their natural, cultural, historical and human heritage. The authors studied examples of best practice in scientific literature and practice, encouraging the development of cross-border tourism and GWs in Europe and Russia, in order to further adapt it to other continents. Analyzing the environmental, economic, social and institutional factors in the region and their role in sustainable development, the need for institutional regulation that would allow the development of a wider development of GWs is identified. Research results reveal sustainable development dilemmas of positive socioeconomic effects of GWs and negative environmental effects of increased flows of tourists. Focus groups and expert interviews allowed us to assess the level of various factors contributing to sustainable development and clarify the directions of the future research.publishersversionPeer reviewe

Hydroxyproline-based DNA mimics provide an efficient gene silencing in vitro and in vivo

To be effective, antisense molecules should be stable in biological fluids, non-toxic, form stable and specific duplexes with target RNAs and readily penetrate through cell membranes without non-specific effects on cell function. We report herein that negatively charged DNA mimics representing chiral analogues of peptide nucleic acids with a constrained trans-4-hydroxy-N-acetylpyrrolidine-2-phosphonate backbone (pHypNAs) meet these criteria. To demonstrate this, we compared silencing potency of these compounds with that of previously evaluated as efficient gene knockdown molecules hetero-oligomers consisting of alternating phosphono-PNA monomers and PNA-like monomers based on trans-4-hydroxy-L-proline (HypNA-pPNAs). Antisense potential of pHypNA mimics was confirmed in a cell-free translation assay with firefly luciferase as well as in a living cell assay with green fluorescent protein. In both cases, the pHypNA antisense oligomers provided a specific knockdown of a target protein production. Confocal microscopy showed that pHypNAs, when transfected into living cells, demonstrated efficient cellular uptake with distribution in the cytosol and nucleus. Also, the high potency of pHypNAs for down-regulation of Ras-like GTPase Ras-dva in Xenopus embryos was demonstrated in comparison with phosphorodiamidate morpholino oligomers. Therefore, our data suggest that pHypNAs are novel antisense agents with potential widespread in vitro and in vivo applications in basic research involving live cells and intact organisms

Thermomagnetic and magnetocaloric properties of metamagnetic Ni-Mn-In-Co Heusler alloy in magnetic fields up to 140 kOe

High cooling power of magnetocaloric refrigeration can be achieved only at large amounts of heat, which can be transferred in one cycle from cold end hot end at quasi-isothermal conditions. The simple and robust experimental method of direct measuring of the transferred heat of materials with magnetocaloric effect (MCE) in thermal contact with massive copper block with definite heat capacity in quasi-isothermal regime was proposed. The vacuum calorimeter for the specific transferred heat ∆Q and adiabatic temperature change ∆T measurements of MCE materials in the fields of Bitter coil magnet up to H = 140 kOe was designed and tested on samples of Ni43Mn37.9In12.1Co7 Heusler alloy with inverse MCE in the vicinity of meta-magnetostructural phase transition (PT). It was found, that the magnetic field H = 80 kOe produces complete PT from martensite to austenite with ∆Q = - 1600 J/kg at initial temperature 273 K

The effects of hypoxia on zooplankton population estimates and migration in lakes

Many zooplankton species typically exhibit diel vertical migration (DVM), where zooplankton migrate from the hypolimnion to the epilimnion of lakes at night. Zooplankton exhibit this behavior to avoid visual predators and UV radiation by remaining in the bottom waters during the day and ascending to the surface waters to feed on phytoplankton at night. However, hypoxic conditions in the hypolimnion of lakes mayinterfere with DVM and force zooplankton to increase diel horizontal migration (DHM) to find predation refuge in littoral zones. Climate change and eutrophication are expected to increase the prevalence and severity of hypoxic conditions worldwide and thereby possibly alter zooplankton migration patterns. We hypothesize that hypoxia will force zooplankton to shift their migration patterns from predominantly DVM to DHM to avoid oxygen-depleted bottom waters. To test our hypothesis, we are conducting a standardized global sampling program to test whether pelagic, full water column estimates of zooplankton are greater at night versus the day under hypolimnetic hypoxic versus oxic conditions. Participants are aiming to sample at least one lake with an oxic hypolimnion and one lake with a hypoxic hypolimnion during the thermally-stratified period at midday and midnight. With our global dataset (currently expecting about 60 lakes in 22 countries), our goal is to improve our understanding of how global change may alter zooplankton migration behavior and patterns in lakes.info:eu-repo/semantics/publishedVersio

Slaughter weight rather than sex affects carcass cuts and tissue composition of Bisaro pigs

Carcass cuts and tissue composition were assessed in Bisaro pigs (n=64) from two sexes (31 gilts and 33 entire males) reared until three target slaughter body-weights (BW) means: 17 kg, 32 kg, and 79 kg. Dressing percentage and backfat thickness increased whereas carcass shrinkage decreased with increasing BW. Slaughter weight affected most of the carcass cut proportions, except shoulder and thoracic regions. Bone proportion decreased linearly with increasing slaughter BW, while intermuscular and subcutaneous adipose tissue depots increased concomitantly. Slaughter weight increased the subcutaneous adipose tissue proportion but this impaired intramuscular and intermuscular adipose tissues in the loin primal. The sex of the pigs minimally affected the carcass composition, as only the belly weight and the subcutaneous adipose tissue proportions were greater in gilts than in entire males. Light pigs regardless of sex are recommended to balance the trade-offs between carcass cuts and their non-edible compositional outcomes.Work included in the Portuguese PRODER research Project BISOPORC – Pork extensive production of Bísara breed, in two alternative systems: fattening on concentrate vs chesnut, Project PRODER SI I&DT Medida 4.1 “Cooperação para a Inovação”. The authors are grateful to Laboratory of Carcass and Meat Quality of Agriculture School of Polytechnic Institute of Bragança ‘Cantinho do Alfredo’. The authors are members of the MARCARNE network, funded by CYTED (ref. 116RT0503).info:eu-repo/semantics/publishedVersio

Features, Opportunities and Problems of Decarbonization of the Russian Arctic

The relevance of the study is determined by the fact that climate mitigation and increased interest in the development of the Arctic, accompanied by state support, gives impetus to the development of new industrial projects, social and industrial infrastructure. As a result of the increased anthropogenic impact, there has been a trend towards an increase in greenhouse gas emissions and disruption of the fragile ecological balance of the Arctic territories. It was revealed that carbon pollution in the Arctic has its own characteristics associated with natural and anthropogenic causes. The low ability of Arctic ecosystems to absorb greenhouse gases, on the one hand, and the need to reduce the cost of production of Arctic enterprises in the current conditions, on the other hand, predetermined the need for CO2 sequestration in the Arctic zone of the Russian Federation. It is substantiated that the current deterrents for the decarbonization of the Arctic are geopolitical risks and sanctions pressure from unfriendly countries

Deterrents to Participation in Sharing Economy Activities: Cross-Country Survey

Research background: Sharing economy is driven by a number of factors, such as intensified application of internet and smartphones, shift towards circular economy and sustainability, and globalization. An impact of globalization processes on consumer society is expressed not only in growth of international trade or development of transnational corporations, but also in change of cultural and communication patterns, specifically regarding change in attitudes towards ownership. Purpose of the article: The goal of the research is to evaluate consumers’ perception of a sharing economy. The current research continues the previous studies conducted by the authors but focuses on reasons for consumers’ negative attitude towards sharing economy. Methods: The study is conducted on the basis of survey results, which include 876 valid questionnaires. To understand the relationship between personal characteristics and lack of activity in sharing economy, the study implemented moderation statistical analysis. The choice of moderators was based on theoretical ground that estimates age, gender and education to influence person's choice on sharing economy; in this study those predictions are testing by means of moderation analysis. Findings & Value added: The authors tested the moderation effect of age, gender, and education on withdrawal from the sharing economy practices in relation to key sharing economy sectors (respondent was involved as service receiver/provider). Besides, the moderation effect of respondent's involvement into sharing economy as provider and receiver on withdrawal from the sharing economy practices in relation to key personal characteristics of the respondent was tested

Human impact on organic matter distribution in the Moskva River

In 2019, we conducted an integrated study on the Moskva River and its tributaries during the low summer season with a focus on organic matter content (OM) assessment in river waters. The maximum OM content was measured at the river headwaters and related to natural sources. The Mozhaysk Reservoir regulation in the summer had the effect of increased organic load below the dam due to a rise in the allochthonous labile OM. Upstream from the Moscow City, the OM content was relatively low, despite wastewater inflow from several densely populated areas and polluted river inflow. Within the city, organic matter concentration increased by a factor of 1.5 due to an inflow from the Volga River via the Moskva-Volga Canal, whereas the release of treated sewage from the Moscow City wastewater treatment facilities did not have a significant effect. Below the city, the OM content increased again by a factor of 1.5 due to the inflow of urban and industrial wastewater and polluted tributaries. The observations in the lower reaches of the Moskva River indicate a high degree of anthropogenic euthrophication